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EVALUATION OF THE PHYTOCHEMICAL COMPOSITION AND ANTIBACTERIAL POTENTIAL OF ETHANOLIC AND AQUEOUS BRYOPHYLLUM PINNATUM (MIRACLE LEAF) EXTRACTS AGAINST FOOD-BORNE PATHOGENS
Authored By: Ohaegbu, C. G., , Onwuakor, C. E., Onuoha, T. N. , Ngene , A. C., Alisigwe, C. V.
Article Number: 1741276570
Received Date: February 18th 2025 Published Date: March 6th 2025Copyright © 2020 Author(s) retain the copyright of this article.
Bryophyllum pinnatum is used in the treatment of different ailments. The present study investigated the phytochemical composition of Bryophyllum pinnatum and evaluated its antibacterial activities against some selected food-borne pathogens. Extracts were obtained using ethanol, and water as solvents and the phytochemical composition was qualitatively determined using conventional methods. The antibacterial activities were done using the tetrazolium microplate assay method and agar well diffusion method. Seven bioactive phytochemical compounds were identified in the extracts. Alkaloids and flavonoids (+++) were the dominant compounds in the ethanolic extracts while tannin (+++) was dominant in the aqueous extracts. The extracts exhibited significant antibacterial activity against some selected food-borne pathogens. The results of this study show that Bryophyllum pinnatum possesses some antibacterial properties and can be used to prevent and treat infections caused by sensitive bacteria.
Ohaegbu, C. G., Onwuakor, C. E., Onuoha, T. N., Ngene A. C., & Alisigwe, C.V. (2025). Evaluation of the Phytochemical Composition and Antibacterial Potential of Ethanolic and Aqueous Bryophyllum pinnatum (Miracle leaf) Extracts Against Food-Borne Pathogens. Journal of Science, Technology, and Education (JSTE); www.nsukjste.com/ 9(4), 46-60
- Ohaegbu, C. G.,
- Department of Microbiology, Michael Okpara University of Agriculture, Umudike
- Onwuakor, C. E.
- Department of Microbiology, Michael Okpara University of Agriculture, Umudike
- Onuoha, T. N.
- Department of Microbiology, Michael Okpara University of Agriculture, Umudike
- Ngene , A. C.
- Department of Microbiology, Michael Okpara University of Agriculture, Umudike
- Alisigwe, C. V.
- Bioscience Institute, Newcastle University, United Kingdom